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Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli

Nucleotide excision repair is able to identify and remove a wide range of DNA helix distorting lesions from the genome. Here the authors use single molecule imaging of UvrA and UvrB molecules and suggest a two-step ‘scan and recruit’ model for UvrA function.

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Autors principals: Mathew Stracy, Marcin Jaciuk, Stephan Uphoff, Achillefs N. Kapanidis, Marcin Nowotny, David J. Sherratt, Pawel Zawadzki
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2016-08-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/ncomms12568
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