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Identification and functional characterization of lncRNAs involved in human monocyte-to-macrophage differentiation

Although long noncoding RNAs (lncRNAs) constitute the majority of the human transcriptome, the functional roles of most remain elusive. While protein-coding genes in macrophage biology have been extensively studied, the contribution of lncRNAs in this context is poorly understood. Given the vast num...

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Principais autores: Christy Montano, Sergio Covarrubias, Eric Malekos, Sol Katzman, Susan Carpenter
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2024-12-01
Serier:RNA Biology
Fag:
Long noncoding RNAs
macrophage
monocyte
differentiation
CRISPR screening
Online adgang:https://www.tandfonline.com/doi/10.1080/15476286.2024.2417155
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