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Modeling the Competition between Misfolded Aβ Conformers That Produce Distinct Types of Amyloid Pathology in Alzheimer’s Disease

The amyloid pathology characteristic of Alzheimer’s disease (AD) can be broadly classified as either fibrillary amyloid or diffuse amyloid. Fibrillary amyloid is found in cored-neuritic deposits, fibrillar deposits, and vascular deposits, and binds strongly to the amyloid revealing dyes Thioflavin-S...

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書誌詳細
主要な著者: Guilian Xu, Susan Fromholt, David R. Borchelt
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2022-06-01
シリーズ:Biomolecules
主題:
オンライン・アクセス:https://www.mdpi.com/2218-273X/12/7/886
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