The immunoglobulin A isotype of the Arabian camel (Camelus dromedarius) preserves the dualistic structure of unconventional single-domain and canonical heavy chains

IntroductionThe evolution of adaptive immunity in Camelidae resulted in the concurrent expression of classic heterotetrameric and unconventional homodimeric heavy chain-only IgG antibodies. Heavy chain-only IgG bears a single variable domain and lacks the constant heavy (CH) γ1 domain required for p...

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Bibliografiska uppgifter

Huvudupphov:	Walter Conca, Soad M. Saleh, Rana Al-Rabiah, Ranjit Singh Parhar, Mahmoud Abd-Elnaeim, Hussein Al-Hindas, Alexander Tinson, Katharina Birgit Kroell, Klaus Roman Liedl, Kate Collison, Uday Kishore, Futwan Al-Mohanna
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Frontiers Media S.A. 2023-12-01
Serie:	Frontiers in Immunology
Ämnen:	Arabian camel immunoglobulin A heavy chain-only IgA unconventional IgA heavy chain IgA variable heavy heavy (VHH) domain third eyelid mucosal immunity
Länkar:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1289769/full
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