Succinate promotes pulmonary fibrosis through GPR91 and predicts death in idiopathic pulmonary fibrosis

Abstract Idiopathic pulmonary fibrosis (IPF) is believed to be associated with a notable disruption of cellular energy metabolism. By detecting the changes of energy metabolites in the serum of patients with pulmonary fibrosis, we aimed to investigate the diagnostic and prognostic value of energy me...

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Detalhes bibliográficos

Principais autores:	Yijun He, Yuanyuan Han, Lijun Zou, Tingting Yao, Yan Zhang, Xin Lv, Mao Jiang, Lingzhi Long, Mengyu Li, Xiaoyun Cheng, Guoliang Jiang, Zhangzhe Peng, Lijian Tao, Jie Meng, Wei Xie
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-06-01
coleção:	Scientific Reports
Assuntos:	Idiopathic pulmonary fibrosis Energy metabolism Succinate GPR91
Acesso em linha:	https://doi.org/10.1038/s41598-024-64844-5
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