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Cysteine imaging reveals early redox dysregulation and identifies gnetol as a ferroptosis-modulating agent in doxorubicin cardiotoxicity

Doxorubicin (DOX)-induced cardiotoxicity remains a major limitation of cancer chemotherapy, largely due to the lack of sensitive approaches for early detection and effective cardioprotective interventions. This study investigated whether cysteine depletion represents an early redox event during DOX...

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Autors principals: Yan Chen, Bo Zhang, Yufan Wei, Yanfa Dai, Baoyue Zhang, Jing Li, Ke-Jia Wu, Ning Sun, Chenwen Shao
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2026-05-01
Col·lecció:Redox Biology
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S2213231726001291
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