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Heterozygosity for fibrinogen results in efficient resolution of kidney ischemia reperfusion injury.

Fibrinogen (Fg) has been recognized to play a central role in coagulation, inflammation and tissue regeneration. Several studies have used Fg deficient mice (Fg(-/-)) in comparison with heterozygous mice (Fg(+/-)) to point the proinflammatory role of Fg in diverse pathological conditions and disease...

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Autors principals: Amrendra Kumar Ajay, Janani Saikumar, Vanesa Bijol, Vishal S Vaidya
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2012-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3446934?pdf=render
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