Design of diverse, functional mitochondrial targeting sequences across eukaryotic organisms using variational autoencoder
Abstract Mitochondria play a key role in energy production and metabolism, making them a promising target for metabolic engineering and disease treatment. However, despite the known influence of passenger proteins on localization efficiency, only a few protein-localization tags have been characteriz...
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| Principais autores: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2025-05-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-025-59499-3 |
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