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Homeostatic cytokines reciprocally modulate the emergence of prenatal effector PLZF+CD4+ T cells in humans

The development of human prenatal adaptive immunity progresses faster than previously appreciated, with the emergence of memory CD4+ T cells alongside regulatory T cells by midgestation. We previously identified a prenatal specific population of promyelocytic leukemia zinc finger–positive (PLZF+) CD...

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Príomhchruthaitheoirí: Veronica Locher, Sara Park, Daniel G. Bunis, Stephanie Makredes, Margareta Mayer, Trevor D. Burt, Gabriela K. Fragiadakis, Joanna Halkias
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: American Society for Clinical investigation 2023-11-01
Sraith:JCI Insight
Ábhair:
Rochtain ar líne:https://doi.org/10.1172/jci.insight.164672
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