Co-expression of PD1+ and HLA-DR+ in CD8+ T cells is increased in tonsils of children with EBV primary and persistent infection

IntroductionEpstein–Barr virus (EBV) infects B lymphocytes and establishes lifelong persistence in the B cells. While systemic T-cell responses have been well characterized, the local immune response at the site of viral entry in children from undeveloped countries remains poorly understood.MethodsT...

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Principais autores:	María Eugenia Amarillo, Karen Lindl, Veronica Lapido, Ignacio E. Rojas Campión, M. Soledad Collado, Johanna Speratti, Andrea Valerio, Plácida Baz, Elena De Matteo, L. Ariel Billordo, Paola Chabay
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-09-01
coleção:	Frontiers in Immunology
Assuntos:	EBV tonsil children CD4+ T cell CD8+ T cells
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1653165/full
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