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Drug-resistant gram-negative bacterial infections in children in the Oceania region: review of the epidemiology, antimicrobial availability, treatment, clinical trial and pharmacokinetic data, and key evidence gaps

Summary: Gram-negative bacterial infections remain a major cause of morbidity and mortality in children and neonates globally, compounded by the rise of antimicrobial resistance. Barriers to paediatric antibiotic licencing lead to reduced availability of potentially effective agents for treatment. F...

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Principais autores: Daniel K. Yeoh, Alison Boast, Sophie CH. Wen, Phoebe CM. Williams, Lesley Voss, Brett Ritchie, Mona Mostaghim, Flora Lutui, Alice Lei, Tony Lai, Adam D. Irwin, Kiera Harwood, Thomas Ewin, Celia Cooper, Emma Best, Sarah Bannister, Amanda Gwee, Sean Beggs, Asha Bowen, Jeremy Carr, Te Yu Hung, Ulrik Lorenzen, Brendan McMullan, Bradley Rockliff, Thomas Snelling, Tony Walls, Heather Weerdenburg, Amanda Wilkins
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-11-01
Serier:The Lancet Regional Health. Western Pacific
Fag:
Gram-negative
Drug-resistant
ESBL
Carbapenem-resistant
Paediatric
Children
Online adgang:http://www.sciencedirect.com/science/article/pii/S2666606525002743
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