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Proteins with complex architecture as potential targets for drug design: a case study of Mycobacterium tuberculosis.

Lengthy co-evolution of Homo sapiens and Mycobacterium tuberculosis, the main causative agent of tuberculosis, resulted in a dramatically successful pathogen species that presents considerable challenge for modern medicine. The continuous and ever increasing appearance of multi-drug resistant mycoba...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Bálint Mészáros, Judit Tóth, Beáta G Vértessy, Zsuzsanna Dosztányi, István Simon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2011-07-01
Schriftenreihe:PLoS Computational Biology
Online-Zugang:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002118&type=printable
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