Large-Scale Functional RNAi Screen in Identifies TGF-β and Notch Signaling Pathways as Modifiers of
Variants in CACNA1A that encodes the pore-forming α 1 -subunit of human voltage-gated Cav2.1 (P/Q-type) Ca 2+ channels cause several autosomal-dominant neurologic disorders, including familial hemiplegic migraine type 1, episodic ataxia type 2, and spinocerebellar ataxia type 6. To identify modifier...
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| Principais autores: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2016-03-01
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| Serier: | ASN Neuro |
| Online adgang: | https://doi.org/10.1177/1759091416637025 |
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