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Cholesterol: A modulator of the phagocyte NADPH oxidase activity - A cell-free study

The NADPH oxidase Nox2, a multi-subunit enzyme complex comprising membrane and cytosolic proteins, catalyzes a very intense production of superoxide ions O2•−, which are transformed into other reactive oxygen species (ROS). In vitro, it has to be activated by addition of amphiphiles like arachidonic...

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Bibliografiske detaljer
Principais autores: Rawand Masoud, Tania Bizouarn, Chantal Houée-Levin
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2014-01-01
Serier:Redox Biology
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Online adgang:http://www.sciencedirect.com/science/article/pii/S2213231714001074
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