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Identification of MUC5B as a lymph node metastasis-associated gene in lung adenocarcinoma through integrated transcriptomic and machine learning approaches

BackgroundLung adenocarcinoma (LUAD) is the most prevalent subtype of lung cancer, with lymph node metastasis serving as a key prognostic factor. MUC5B, a member of the mucin family, has been implicated in the progression of various cancers, yet its specific role in LUAD metastasis remains underexpl...

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Principais autores: Weijian Song, Qian Yang, Minjun Du, Jiacong Wei, Boxuan Zhou, Jianwei Shi, Linchuan Liang, Zixu Liu, Mei Liang, Mianyang Li, Yushun Gao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-12-01
coleção:Frontiers in Immunology
Assuntos:
MUC5B
lung adenocarcinoma
lymph node metastasis
prognosis
machine learning
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1666240/full
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