The mesodermal and myogenic specification of hESCs depend on ZEB1 and are inhibited by ZEB2
Summary: Human embryonic stem cells (hESCs) can differentiate into any cell lineage. Here, we report that ZEB1 and ZEB2 promote and inhibit mesodermal-to-myogenic specification of hESCs, respectively. Knockdown and/or overexpression experiments of ZEB1, ZEB2, or PAX7 in hESCs indicate that ZEB1 is r...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2023-10-01
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| Серии: | Cell Reports |
| Предметы: | |
| Online-ссылка: | http://www.sciencedirect.com/science/article/pii/S2211124723012342 |
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