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Role of heparin in pulmonary cell populations in an in-vitro model of acute lung injury

Abstract Background In the early stages of acute respiratory distress syndrome (ARDS), pro-inflammatory mediators inhibit natural anticoagulant factors and initiate an increase in procoagulant activity. Previous studies proved the beneficial effects of heparin in pulmonary coagulopathy, which derive...

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Uloženo v:
Hlavní autoři: Marta Camprubí–Rimblas, Raquel Guillamat-Prats, Thomas Lebouvier, Josep Bringué, Laura Chimenti, Manuela Iglesias, Carme Obiols, Jessica Tijero, Lluís Blanch, Antonio Artigas
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2017-05-01
Edice:Respiratory Research
Témata:
Acute Respiratory Distress Syndrome (ARDS)
Alveolar macrophages
Alveolar cells
Fibroblasts
Anticoagulants
Inflammation
On-line přístup:http://link.springer.com/article/10.1186/s12931-017-0572-3
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