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GWAS and polygenic risk score of severe COVID-19 in Eastern Europe

BackgroundCOVID-19 disease has infected more than 772 million people, leading to 7 million deaths. Although the severe course of COVID-19 can be prevented using appropriate treatments, effective interventions require a thorough research of the genetic factors involved in its pathogenesis.MethodsWe c...

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Autori principali: Elena Kovalenko, Layal Shaheen, Ekaterina Vergasova, Alexey Kamelin, Valerya Rubinova, Dmitry Kharitonov, Anna Kim, Nikolay Plotnikov, Artem Elmuratov, Natalia Borovkova, Maya Storozheva, Sergey Solonin, Irina Gilyazova, Petr Mironov, Elza Khusnutdinova, Sergey Petrikov, Anna Ilinskaya, Valery Ilinsky, Alexander Rakitko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2024-09-01
Serie:Frontiers in Medicine
Soggetti:
COVID-19
GWAS
polygenic risk score
severe COVID-19
LZTFL1 gene
Accesso online:https://www.frontiersin.org/articles/10.3389/fmed.2024.1409714/full
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