Lactylation-related gene AKR1A1 contributes to osteoporosis via metabolic–immune regulation: evidence from multi-omics integration, single-cell transcriptomics, and in vitro validation
ObjectiveThis study aimed to systematically identify key differentially expressed genes (DEGs) associated with lysine lactylation in osteoporosis and to explore their potential roles in disease pathogenesis from a dual perspective of metabolic and immune regulation, thereby providing a theoretical b...
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| Principais autores: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Frontiers Media S.A.
2025-10-01
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| 叢編: | Frontiers in Immunology |
| 主題: | |
| 在線閱讀: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1680305/full |
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