Dual Inhibition of Phosphodiesterase 3 and 4 Enzymes by Ensifentrine Protects against MRSA-Induced Lung Endothelial and Epithelial Dysfunction

Acute Respiratory Distress Syndrome (ARDS) is a severe lung condition with a high mortality rate for which there are no effective therapeutics. The failure of the alveolar–capillary barrier, composed of lung endothelial (EC) and alveolar epithelial (AEC) cells, is a critical factor leading to excess...

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Principais autores:	Mohammed Yaman Al Matni, Lucille Meliton, Steven M. Dudek, Eleftheria Letsiou
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2024-10-01
coleção:	Cells
Assuntos:	ARDS acute lung injury ensifentrine RPL554 phosphodiesterase permeability
Acesso em linha:	https://www.mdpi.com/2073-4409/13/21/1750
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