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Production of the Invasive Aspergillosis Biomarker Bis(methylthio)gliotoxin Within the Genus Aspergillus: In Vitro and in Vivo Metabolite Quantification and Genomic Analysis

Gliotoxin (GT) is a fungal secondary metabolite that has attracted great interest due to its high biological activity since it was discovered by the 1930s. An inactive derivative of this molecule, bis(methylthio)gliotoxin (bmGT), has been proposed as an invasive aspergillosis (IA) biomarker. Neverth...

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Principais autores: Matxalen Vidal-García, Sergio Redrado, M. Pilar Domingo, Patricia Marquina, Cristina Colmenarejo, Jacques F. Meis, Antonio Rezusta, Julian Pardo, Eva M. Galvez
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2018-06-01
סדרה:Frontiers in Microbiology
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גישה מקוונת:https://www.frontiersin.org/article/10.3389/fmicb.2018.01246/full
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