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Non-invasive in vivo imaging of porcine islet xenografts in a preclinical model with [68Ga]Ga-exendin-4

IntroductionIslet xenotransplantation may be a therapeutic option in type 1 diabetes. Recent advances in generating genetically modified source pigs offer advantages as immune suppressants can potentially be eliminated after the transplantation. Therapy monitoring would greatly benefit from noninvas...

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Huvudupphov: Felix Lindheimer, Magdalena Julia Lindner, Rosel Oos, Mohsen Honarpisheh, Yichen Zhang, Yutian Lei, Lelia Wolf-van Buerck, Franz Josef Gildehaus, Simon Lindner, Peter Bartenstein, Elisabeth Kemter, Eckhard Wolf, Jochen Seissler, Sibylle Ziegler
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2023-05-01
Serie:Frontiers in Nuclear Medicine
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Länkar:https://www.frontiersin.org/articles/10.3389/fnume.2023.1157480/full
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