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Histone Deacetylase Inhibition Enhances AQP3 Levels in Human Corneal Epithelial Cells and Corneal Wound Healing in Normoglycemic and Diabetic Male Mice

Corneal problems, such as delayed and incomplete wound repair, are frequent in diabetes, affecting up to 70% of diabetic patients. In skin, histone deacetylases (HDACs) have been previously found to repress expression of the glycerol channel aquaporin-3 (AQP3), the deficiency of which delays corneal...

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Bibliografische Detailangaben
Hauptverfasser: Samuel Melnyk, Xiaowen Lu, Victoria Ronderos, Vivek Choudhary, Maribeth H. Johnson, Mitchell A. Watsky, Wendy B. Bollag
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2025-11-01
Schriftenreihe:Cells
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Online-Zugang:https://www.mdpi.com/2073-4409/14/23/1880
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