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Rosuvastatin Upregulates RCOR1 to Repress C10ORF10 Transcription and Alleviate Oxidative Stress and Plaque Formation in Atherosclerosis

ABSTRACT Rosuvastatin (RVS) is an HMG‐CoA reductase inhibitor with lipid‐lowering properties. This study aims to investigate the role of RVS in plaque formation in atherosclerosis (AS) and its functional mechanism. ApoE−/− mice were fed a high‐fat diet to generate a mouse model of AS. RVS treatment...

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Principais autores: Xin Fu, Chuang Liu, Ya‐Li Chen, Jie‐Lin Qin, Ting‐Ting Wang, Shan‐Shan Fu
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2026-03-01
Serier:Kaohsiung Journal of Medical Sciences
Fag:
atherosclerosis
C10ORF10
HVSMCs
RCOR1
rosuvastatin
Online adgang:https://doi.org/10.1002/kjm2.70106
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