Genetic insights and therapeutic avenues: unraveling the role of polyunsaturated fatty acids as mediators between hypothyroidism and Von Willebrand disease through Mendelian randomization

BackgroundPrevious observational studies have shown that Hypothyroidism is associated with Von Willebrand Disease (VWD), but the causal relationship has not been confirmed because of conflicting findings and confounding by mixing factors. There are also some studies suggesting that polyunsaturated f...

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Detalhes bibliográficos

Principais autores:	Wenting Zhou, Rui He, Ruwei Ou
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-01-01
coleção:	Frontiers in Genetics
Assuntos:	hypothyroidism Von Willebrand disease polyunsaturated fatty acids Mendelian randomization study mediation analysis
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fgene.2024.1426401/full
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