An essential, kinetoplastid-specific GDP-Fuc: β-D-Gal α-1,2-fucosyltransferase is located in the mitochondrion of Trypanosoma brucei

Fucose is a common component of eukaryotic cell-surface glycoconjugates, generally added by Golgi-resident fucosyltransferases. Whereas fucosylated glycoconjugates are rare in kinetoplastids, the biosynthesis of the nucleotide sugar GDP-Fuc has been shown to be essential in Trypanosoma brucei. Here...

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Autors principals:	Giulia Bandini, Sebastian Damerow, Maria Lucia Sempaio Guther, Hongjie Guo, Angela Mehlert, Jose Carlos Paredes Franco, Stephen Beverley, Michael AJ Ferguson
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2021-08-01
Col·lecció:	eLife
Matèries:	kinetoplastid glycobiology mitochondria fucosyltranferase Trypanosoma
Accés en línia:	https://elifesciences.org/articles/70272
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