Cruzipain and Its Physiological Inhibitor, Chagasin, as a DNA-Based Therapeutic Vaccine Against Trypanosoma cruzi

Chagas disease caused by the protozoan parasite Trypanosoma cruzi is endemic in 21 Latin American countries and the southern United States and now is spreading into several other countries due to migration. Despite the efforts to control the vector throughout the Americas, currently, there are almos...

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Hlavní autoři:	Natacha Cerny, Augusto Ernesto Bivona, Andrés Sanchez Alberti, Sebastián Nicolás Trinitario, Celina Morales, Alejandro Cardoso Landaburu, Silvia Inés Cazorla, Emilio Luis Malchiodi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2020-10-01
Edice:	Frontiers in Immunology
Témata:	Chagas disease Trypanosoma cruzi cruzipain chagasin GM-CSF therapeutic vaccine
On-line přístup:	https://www.frontiersin.org/article/10.3389/fimmu.2020.565142/full
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