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A paradigm for virus-host coevolution: sequential counter-adaptations between endogenous and exogenous retroviruses.

Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections of the host germline transmitted vertically from generation to generation. It is hypothesized that some ERVs are used by the host as restriction factors to block the infection of pathogenic retroviruses. Indeed, some ERVs e...

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Autors principals: Frederick Arnaud, Marco Caporale, Mariana Varela, Roman Biek, Bernardo Chessa, Alberto Alberti, Matthew Golder, Manuela Mura, Ya-Ping Zhang, Li Yu, Filipe Pereira, James C Demartini, Kreg Leymaster, Thomas E Spencer, Massimo Palmarini
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2007-11-01
Col·lecció:PLoS Pathogens
Accés en línia:https://doi.org/10.1371/journal.ppat.0030170
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