A Facile Synthesis of Some Bioactive Isoxazoline Dicarboxylic Acids via Microwave-Assisted 1,3-Dipolar Cycloaddition Reaction

The microwave-assisted 1,3-dipolar cycloaddition reaction of several aldoximes and dimethyl-2-methylene glutarate in the presence of diacetoxyiodobenzene as an oxidant produced four new isoxazoline-derived dimethyl carboxylates. Saponification followed by acidification of the latter yielded novel is...

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Autors principals:	Jessica Master, Shekiel Sydney, Harsha Rajapaske, Malek Saffiddine, Vikiana Reyes, Richard W. Denton
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2024-12-01
Col·lecció:	Reactions
Matèries:	microwave-assisted 1,3-dipolar cycloaddition reaction isoxazoline antibiotics saponofication
Accés en línia:	https://www.mdpi.com/2624-781X/5/4/57
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