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Combinatorial in situ cancer vaccines: unlocking broad and enhanced antitumor responses

Abstract In situ cancer vaccination, also termed intratumoral immunotherapy, transforms the tumor microenvironment into an endogenous vaccine platform by leveraging the tumor itself as a source of antigens. Unlike conventional tumor-associated antigen (TAA) or personalized neoantigen vaccines that r...

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Autors principals: Weihsuan Chen, Juwon Baig, Hyebeen Choi, Sejin Son
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2026-07-01
Col·lecció:Signal Transduction and Targeted Therapy
Accés en línia:https://doi.org/10.1038/s41392-026-02821-2
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