Expression profiling of DNA methyl transferase I (DNMT1) and efficacy of a DNA-hypomethylating agent (decitabine) in combination with chemotherapy in osteosarcoma

Background: Abnormality in the DNA methylation process is one of the hallmarks of cancer. Emerging evidence strongly supports the idea that defects in DNA methyl transferases (DNMTs) are involved in tumor development and progression. This alteration has major effects at the transcription level of va...

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Principais autores:	Parunya Chaiyawat, Nutnicha Sirikaew, Piyaporn Budprom, Jeerawan Klangjorhor, Areerak Phanphaisarn, Pimpisa Teeyakasem, Jongkolnee Settakorn, Dumnoensun Pruksakorn
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Elsevier 2020-12-01
סדרה:	Journal of Bone Oncology
נושאים:	Osteosarcoma DNA methylation Immunohistochemistry Drug combinations Drug Synergism
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S2212137420300762
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!