Kinetic Transition in Amyloid Assembly as a Screening Assay for Oligomer-Selective Dyes

Assembly of amyloid fibrils and small globular oligomers is associated with a significant number of human disorders that include Alzheimer’s disease, senile systemic amyloidosis, and type II diabetes. Recent findings implicate small amyloid oligomers as the dominant aggregate species mediating...

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Autors principals:	Jeremy Barton, D. Sebastian Arias, Chamani Niyangoda, Gustavo Borjas, Nathan Le, Saefallah Mohamed, Martin Muschol
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2019-09-01
Col·lecció:	Biomolecules
Matèries:	oligomer formation amyloidosis assembly pathway dye fluorescence thioflavin t
Accés en línia:	https://www.mdpi.com/2218-273X/9/10/539
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