Activatable nanoflytrap achieves synergistic “Capture-Block-Regulate” therapy of pancreatic ductal adenocarcinoma

Abstract Pancreatic ductal adenocarcinoma (PDAC) remains one of the most refractory malignancies because of its dense stromal barrier and hypoxic microenvironment. Inspired by the Venus flytrap, we engineered an intelligent nanoflytrap (NT) system that performs a coordinated three stage therapeutic...

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Detalhes bibliográficos

Principais autores:	Kai Guo, Shuai Ren, Yingying Cao, Huifeng Zhang, Jin Cui, Li Xian Yip, Ximing Wang, Ying Tian, Lina Song, Zhongqiu Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-04-01
coleção:	Journal of Nanobiotechnology
Assuntos:	Nanoflytrap Dihydroartemisinin Pancreatic ductal adenocarcinoma Apoptosis Ferroptosis
Acesso em linha:	https://doi.org/10.1186/s12951-026-04420-3
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