Circulating Senescent T Cells Are Linked to Systemic Inflammation and Lesion Size During Human Cutaneous Leishmaniasis

Leishmania (Viannia) braziliensis induces American tegumentary leishmaniasis that ranges in severity from the milder form, cutaneous (CL) to severe disseminated cutaneous leishmaniasis. Patients with CL develop a cell-mediated Th1 immune response accompanied by production of inflammatory cytokines,...

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Главные авторы:	Luciana P. Covre, Régia F. Martins, Oliver P. Devine, Emma S. Chambers, Milica Vukmanovic-Stejic, Juliana A. Silva, Reynaldo Dietze, Rodrigo R. Rodrigues, Herbert L. de Matos Guedes, Aloísio Falqueto, Arne N. Akbar, Daniel C. O. Gomes
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2019-01-01
Серии:	Frontiers in Immunology
Предметы:	cutaneous leishmaniasis immunosenescence inflammation SASP-analogous L. braziliensis T cells
Online-ссылка:	https://www.frontiersin.org/article/10.3389/fimmu.2018.03001/full
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