Associations of estradiol levels and genetic polymorphisms of inflammatory genes with the risk of ischemic stroke

Abstract Background Estrogen plays an important role as an anti-inflammatory and neuroprotective agent in ischemic stroke. In this study, we analyzed the effect of a polygenic risk score (PRS) constructed using inflammatory genes and estradiol levels on the risk of ischemic stroke. Methods This case...

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Hlavní autoři:	Yi-Chen Hsieh, Fang-I Hsieh, Yih-Ru Chen, Chaur-Jong Hu, Jiann-Shing Jeng, Sung-Chun Tang, Nai-Fang Chi, Huey-Juan Lin, Li-Ming Lien, Giia-Sheun Peng, Hung-Yi Chiou, for the Formosa Stroke Genetic Consortium (FSGC)
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2017-03-01
Edice:	Journal of Biomedical Science
Témata:	Ischemic stroke Estradiol Inflammation Polygenic risk score
On-line přístup:	http://link.springer.com/article/10.1186/s12929-017-0332-1
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