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Podocalyxin-like protein as a predictive biomarker for benefit of neoadjuvant chemotherapy in resectable gastric and esophageal adenocarcinoma

Abstract Background We have previously shown that podocalyxin-like protein (PODXL) is a prognostic biomarker for poor survival in gastric and esophageal adenocarcinoma treated with surgery up-front. The aim of the present study was to assess PODXL expression in tumors from patients treated with neoa...

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Principais autores: David Borg, Anna H. Larsson, Charlotta Hedner, Björn Nodin, Anders Johnsson, Karin Jirström
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-10-01
coleção:Journal of Translational Medicine
Assuntos:
Esophageal adenocarcinoma
Gastric adenocarcinoma
Neoadjuvant chemotherapy
PODXL
Acesso em linha:http://link.springer.com/article/10.1186/s12967-018-1668-3
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