A novel patient-derived organoids-based xenografts model for preclinical drug response testing in patients with colorectal liver metastases

Abstract Backgrounds Cancer-related mortality in patients with colorectal cancer (CRC) is predominantly caused by development of colorectal liver metastases (CLMs). How to screen the sensitive chemotherapy and targeted therapy is the key element to improve the prognosis of CLMs patients. The study a...

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Auteurs principaux:	Mi Jian, Li Ren, Guodong He, Qi Lin, Wentao Tang, Yijiao Chen, Jingwen Chen, Tianyu Liu, Meiling Ji, Ye Wei, Wenju Chang, Jianmin Xu
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2020-06-01
Collection:	Journal of Translational Medicine
Sujets:	Colorectal cancer Liver metastases Animal model Organoids
Accès en ligne:	http://link.springer.com/article/10.1186/s12967-020-02407-8
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