Cerebrospinal fluid lactate levels along the Alzheimer’s disease continuum and associations with blood-brain barrier integrity, age, cognition, and biomarkers

Abstract Background Cerebrospinal fluid (CSF) lactate levels have been suggested to be associated with disease severity and progression in several neurological diseases as an indicator of impaired energy metabolism, neuronal death, or microglial activation. Few studies have examined CSF lactate leve...

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Autors principals:	Paul Theo Zebhauser, Achim Berthele, Oliver Goldhardt, Janine Diehl-Schmid, Josef Priller, Marion Ortner, Timo Grimmer
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2022-04-01
Col·lecció:	Alzheimer’s Research & Therapy
Matèries:	Alzheimer’s disease Cerebrospinal fluid Lactate Biomarkers Blood-brain barrier
Accés en línia:	https://doi.org/10.1186/s13195-022-01004-9
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