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Gene polymorphism profiles of drug-metabolising enzymes GSTM1, GSTT1 and GSTP1 in an Argentinian population

Background: Glutathione S-transferases (GSTs) are drug-metabolising enzymes involved in biotransformation of carcinogens, drugs, xenobiotics and oxygen free radicals. Polymorphisms of GST genes contribute to inter-individual and population variability in the susceptibility to environmental risk fact...

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Principais autores: Natalia Weich, Alejandro Roisman, Belén Cerliani, Hilda V. Aráoz, Lilien Chertkoff, Silvina M. Richard, Irma Slavutsky, Irene B. Larripa, Ariela F. Fundia
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2017-05-01
Serier:Annals of Human Biology
Fag:
glutathione s-transferases
polymorphisms
pharmacogenetic markers
human variability
argentinian population
Online adgang:http://dx.doi.org/10.1080/03014460.2016.1259429
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