Effects of catheter-based extradural collagenase chemonucleolysis on pain scores and lumbar function in patients with lumbar disc herniation

AimLumbar disc herniation (LDH) is a leading cause of radicular pain and disability. While conventional intradiscal collagenase chemonucleolysis (ICCN) is a minimally invasive alternative to surgery, it is limited by suboptimal drug targeting and recurrence. Catheter-based extradural collagenase che...

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Autores principales:	Yongfu Feng, Yuanxin Huang, Jie Yuan, Guoping Song, Guanfeng Shang, Qian Zhang, Xiaoyun Luo, Yun Xu
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2026-04-01
Colección:	Frontiers in Medicine
Materias:	catheter extradural collagenase chemonucleolysis lumbar disc herniation lumbar function pain
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fmed.2026.1807178/full
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