Molecular Dynamics Simulation Studies on the Aggregation of Amyloid-β Peptides and Their Disaggregation by Ultrasonic Wave and Infrared Laser Irradiation

Alzheimer’s disease is understood to be caused by amyloid fibrils and oligomers formed by aggregated amyloid-β (Aβ) peptides. This review article presents molecular dynamics (MD) simulation studies of Aβ peptides and Aβ fragments on their aggregation, aggregation inhibition, amyloid fibril conformat...

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Bibliografische Detailangaben

Hauptverfasser:	Hisashi Okumura, Satoru G. Itoh
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-04-01
Schriftenreihe:	Molecules
Schlagworte:	molecular dynamics simulation replica permutation method amyloid-β aggregation disaggregation β-sheet
Online-Zugang:	https://www.mdpi.com/1420-3049/27/8/2483
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