Analyses of the folding sites of irregular β-trefoil fold proteins through sequence-based techniques and Gō-model simulations

Abstract Background The details of the folding mechanisms have not yet been fully understood for many proteins, and it is believed that the information on the folding mechanism of a protein is encoded in its amino acid sequence. β-trefoil proteins are known to have the same 3D scaffold, namely, a th...

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Үндсэн зохиолчид:	Risako Kimura, Panyavut Aumpuchin, Shoya Hamaue, Takumi Shimomura, Takeshi Kikuchi
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2020-04-01
Цуврал:	BMC Molecular and Cell Biology
Нөхцлүүд:	β-Trefoil fold Folding mechanism Inter-residue average distance statistics Conserved hydrophobic residues Gō-model simulation
Онлайн хандалт:	http://link.springer.com/article/10.1186/s12860-020-00271-4
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!