Integrated Molecular Analysis of Thymoquinone–Methotrexate Synergy in Breast Cancer Cells: Apoptosis, Oxidative Stress, and Pathway Modulation

<b>Background/Objectives:</b> Breast cancer remains one of the leading causes of cancer-related mortality in women worldwide, highlighting the urgent need for effective and less toxic therapeutic strategies. Thymoquinone (TQ), a bioactive phytochemical derived from Nigella sativa, possesses antioxid...

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Главные авторы:	Senem Alkan Akalın, Yasemin Afşin, İlhan Özdemir, Mehmet Cudi Tuncer, Şamil Öztürk
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2025-10-01
Серии:	Pharmaceuticals
Предметы:	thymoquinone methotrexate breast cancer MCF-7 apoptosis synergistic effect
Online-ссылка:	https://www.mdpi.com/1424-8247/18/10/1551
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