Angiotensin-(1–7) ameliorates sepsis-induced cardiomyopathy by alleviating inflammatory response and mitochondrial damage through the NF-κB and MAPK pathways

Abstract Background There is no available viable treatment for Sepsis-Induced Cardiomyopathy (SIC), a common sepsis complication with a higher fatality risk. The septic patients showed an abnormal activation of the renin angiotensin (Ang) aldosterone system (RAAS). However, it is not known how the A...

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Principais autores:	Xin-Sen Chen, Jing-Rui Cui, Xiang-Long Meng, Shu-Hang Wang, Wei Wei, Yu-Lei Gao, Song-Tao Shou, Yan-Cun Liu, Yan-Fen Chai
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-01-01
coleção:	Journal of Translational Medicine
Assuntos:	Sepsis-induced cardiomyopathy Mitochondria Angiotensin (1–7) Angiotensin II Oxidative stress Apoptosis
Acesso em linha:	https://doi.org/10.1186/s12967-022-03842-5
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