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Association between Cytochrome P450 2 C9 and Vitamin K Epoxide Reductase Complex Subunit 1 Polymorphisms with Warfarin dose among Iranian Patients

Background: Warfarin is a common anticoagulant drug that has a narrow therapeutic index; higher dose causes excessive bleeding and lower dose leads to cerebrovascular clotting and stroke in patients. Genetic factors that have been associated with warfarin response are the genes of cytochrome P450 2C...

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Uloženo v:
Hlavní autoři: Reyhaneh Kameli, Mandana Hasanzad, Zahra Tahmasebi Fard, Mojgan Babanejad, Mahdieh Imeni, Lotfollah Feizi Barnaji, Atoosa Madadkar, Seyed Hamid Jamaldini
Médium: Artigo
Jazyk:Inglês
Vydáno: Mazandaran University of Medical Sciences and Health Services 2016-11-01
Edice:Research in Molecular Medicine
Témata:
CYP2C9*2
CYP2C9*3
VKORC1
Warfarin
RFLP
On-line přístup:http://rmm.mazums.ac.ir/browse.php?a_code=A-10-26-31&slc_lang=en&sid=1
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