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Sanguinarine Induces H<sub>2</sub>O<sub>2</sub>-Dependent Apoptosis and Ferroptosis in Human Cervical Cancer

Sanguinarine (SNG) is a benzophenanthridine alkaloid isolated mainly from <i>Sanguinaria canadensis</i>, <i>Chelidonium majus</i>, and <i>Macleaya cordata</i>. SNG is considered an antineoplastic agent based on its cytotoxic activity against various tumors. However, the exact molecular mechanism thr...

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Hoofdauteurs: Ameer Alakkal, Faisal Thayyullathil, Siraj Pallichankandy, Karthikeyan Subburayan, Anees Rahman Cheratta, Sehamuddin Galadari
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2022-07-01
Reeks:Biomedicines
Onderwerpen:
apoptosis
ferroptosis
LPO
labile iron
ROS
sanguinarine
Online toegang:https://www.mdpi.com/2227-9059/10/8/1795
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