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Nuclear factor κB as a target for new drug development in myeloid malignancies

The transcription nuclear factor κB (NF-κB) can intervene in oncogenesis through to its capacity to regulate the expression of a large number of genes that regulate apoptosis, cell proliferation and differentiation as well as inflammation, angiogenesis and tumor migration. Impaired NF-κB activity ha...

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Huvudupphov: Daniela Cilloni, Giovanni Martinelli, Francesca Messa, Michele Baccarani, Giuseppe Saglio
Materialtyp: Artigo
Språk:Inglês
Utgiven: Ferrata Storti Foundation 2007-09-01
Serie:Haematologica
Länkar:https://haematologica.org/article/view/4563
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