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Cardioprotective Effects of LCZ696 (Sacubitril/Valsartan) After Experimental Acute Myocardial Infarction

LCZ696 (sacubitril/valsartan) can lower the risk of cardiovascular events in chronic heart failure. However, it is unclear whether LCZ696 can improve prognosis in patients with acute myocardial infarction (MI). The present study shows that LCZ696 can prevent cardiac rupture after MI, probably due to...

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Principais autores: Masanobu Ishii, MD, Koichi Kaikita, MD, PhD, Koji Sato, MD, PhD, Daisuke Sueta, MD, PhD, Koichiro Fujisue, MD, PhD, Yuichiro Arima, MD, PhD, Yu Oimatsu, MD, Tatsuro Mitsuse, MD, Yoshiro Onoue, MD, PhD, Satoshi Araki, MD, PhD, Megumi Yamamuro, MD, PhD, Taishi Nakamura, MD, PhD, Yasuhiro Izumiya, MD, PhD, Eiichiro Yamamoto, MD, PhD, Sunao Kojima, MD, PhD, Shokei Kim-Mitsuyama, MD, PhD, Hisao Ogawa, MD, PhD, Kenichi Tsujita, MD, PhD
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017-12-01
coleção:JACC: Basic to Translational Science
Assuntos:
myocardial infarction
natriuretic peptide
renin-angiotensin-aldosterone
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2452302X17302218
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