Hepatic FGF21 is not required for fasting metabolism but guides protein appetite post energy depletion

Abstract Fasting initiates a coordinated metabolic response to preserve energy balance. As glycogen stores are depleted, the body transitions to mobilizing fatty acids from adipose tissue and generating ketone bodies in the liver to sustain the function of vital organs. A network of hormonal signals...

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Bibliografiske detaljer

Principais autores:	Justine Bruse, Clothilde Marbach, Arnaud Polizzi, Tatiana Landre, Juliette Salvi, Valérie Alquier-Bacquie, Shiou-Ping Chen, Marine Huillet, Clémence Rives, Céline M P Martin, Prunelle Perrier, Fadila Benhamed, Marion Régnier, Stefan Weger, Claire Naylies, Yannick Lippi, Caroline Sommer, Mikael Albin, Frédéric Lasserre, Thierry Levade, Michael Schupp, Laurence Gamet-Payrastre, Léon Kautz, Nicolas Loiseau, Walter Wahli, Sandrine Ellero-Simatos, Céline Cruciani-Guglielmacci, Alexandra Montagner, Alexandre Benani, Catherine Postic, Hervé Guillou, Anne Fougerat
Format:	Artigo
Sprog:	Inglês
Udgivet:	Springer Nature 2026-04-01
Serier:	EMBO Reports
Online adgang:	https://doi.org/10.1038/s44319-026-00790-9
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