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Functional <i>ERAP1</i> Variants Distinctively Associate with Ankylosing Spondylitis Susceptibility under the Influence of <i>HLA-B27</i> in Taiwanese

Epistasis of <i>ERAP1</i> single nucleotide variations (SNVs) and <i>HLA-B27</i> has been linked to ankylosing spondylitis susceptibility (AS). The current study examined how prevalent <i>ERAP1</i> allelic variants (SNV haplotypes) in Taiwan affect ERAP1 functions and AS susceptibility in the presen...

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Hlavní autoři: Chin-Man Wang, Ming-Kun Liu, Yeong-Jian Jan Wu, Jing-Chi Lin, Jian-Wen Zheng, Jianming Wu, Ji-Yih Chen
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2022-08-01
Edice:Cells
Témata:
ankylosing spondylitis
ERAP1
single nucleotide variant
HLA-B27
HLA class I molecules
On-line přístup:https://www.mdpi.com/2073-4409/11/15/2427
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